Email updates

Keep up to date with the latest news and content from Head & Neck Oncology and BioMed Central.

Open Access Review

The feasibility of gene therapy in the treatment of head and neck cancer

Emanuela Vattemi1 and Pier Paolo Claudio23*

Author Affiliations

1 Department of Clinical and Experimental Medicine, Section of Medical Oncology, University of Verona, Piazzale Stefani 1, 37126, Verona, Italy

2 Department of Biochemistry and Microbiology, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25755, USA

3 Department of Surgery, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25755, USA

For all author emails, please log on.

Head & Neck Oncology 2009, 1:3  doi:10.1186/1758-3284-1-3

Published: 12 January 2009

Abstract

Standard approach to the treatment of head and neck cancer include surgery, chemotherapy, and radiation. More recently, dramatic increases in our knowledge of the molecular and genetic basis of cancer combined with advances in technology have resulted in novel molecular therapies for this disease. In particular, gene therapy, which involves the transfer of genetic material to cells to produce a therapeutic effect, has become a promising approach. Clinical trials concerning gene therapy strategies in head and neck cancer as well as combination of these strategies with chemotherapy and radiation therapy will be discussed.