Table 1 |
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Modern methods of oral cytology for oral squamous cell carcinoma |
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Classification |
Analytic method |
Markers |
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|
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|
Cytomorphometry |
Conventional cytologic diagnosis |
Cell morphology |
|
Computer-assisted image |
Cell morphology |
|
|
analysis (OralCDx) |
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|
|
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|
DNA analysis |
DNA image cytometry |
DNA ploidy, DNA methylation |
|
|
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|
Optical diagnosis |
Autofluorescence |
Flavin, tryptophan, elastin, |
|
|
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|
collagen (endogenous fluorophores) |
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Photodynamic diagnosis |
5-Aminolevulinic acid |
|
|
Photofrin |
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Immunophotodiagnosis antibody targeting |
EGFR |
|
|
|
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|
Zygogianni et al. Head & Neck Oncology 2011 3:2 doi:10.1186/1758-3284-3-2 |
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