Head & Neck Oncology

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Open Access Research

Photodynamic therapy and end-stage tongue base cancer: short communication

Waseem Jerjes1,2,3, Tahwinder Upile4,5, Hani Radhi2* and Colin Hopper1,5

Author Affiliations

1 Department of Surgery, University College London, London, UK

2 Oral and Maxillofacial Surgery Unit, AL-Mustansirya University, Baghdad, Iraq

3 Academic Department of Trauma and Orthopaedic Surgery, School of Medicine, University of Leeds, Leeds, UK

4 Department of Otolaryngology/Head and Neck Surgery, Chase Farm & Barnet NHS Trust, Enfield, UK

5 Head & Neck Unit, University College London Hospital, London, UK

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Head & Neck Oncology 2011, 3:49 doi:10.1186/1758-3284-3-49

Published: 7 December 2011

Abstract

We previously reported on the outcome of 21 patients with stage IV advanced and/or recurrent tongue base carcinoma subjected to mTHPC-PDT. We continue to develop on the previous work by treating more patients with this unforgiving disease. PDT has shown to be a very successful minimally-invasive surgical tool in managing this pathology. Tumour-associated symptoms were reduced significantly. The overall morbidity and mortality following PDT, in this group of patients, were far less when compared with other conventional modalities.